Women’s pathways into and experiences of homelessness differ from those of men. Growing international evidence demonstrates that there is a complex, gender-specific dimension to women’s homelessness and a gender lens needs to be applied to any strategy that aims to prevent and end homelessness for women. Gender lens means acknowledging the specific challenges associated with gender and it should be part of any solution to women’s homelessness. This guide shines a light on the nuances of women’s paths into and experiences of homelessness so that effective gender-responsive support and solutions for women experiencing homelessness might be developed.